INT322473

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.76
Pain Relevance 2.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (DCN) aging (DCN) extracellular region (DCN)
proteinaceous extracellular matrix (DCN)
DCN (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 6 99.90 Very High Very High Very High
withdrawal 60 99.36 Very High Very High Very High
Paracetamol 58 99.30 Very High Very High Very High
Inflammation 2 97.36 Very High Very High Very High
Analgesic 4 94.32 High High
lidocaine 36 93.88 High High
Pain 58 84.56 Quite High
c fibre 2 75.00 Quite High
algogenic 2 72.12 Quite High
bradykinin 2 70.08 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 97.36 Very High Very High Very High
Pain 62 84.56 Quite High
Wheal 4 20.92 Low Low
Pressure And Volume Under Development 4 20.64 Low Low
Unconsciousness 6 5.00 Very Low Very Low Very Low
Cough 2 5.00 Very Low Very Low Very Low
Complex Regional Pain Syndromes 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lee et al. [16] showed that acetaminophen selectively suppresses peripheral PG E2 release and increases COX-2 gene expression in a clinical model of acute inflammation.
Localization (release) of PG E2 associated with paracetamol and inflammation
1) Confidence 0.03 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2908220 Disease Relevance 0.47 Pain Relevance 1.57
Further studies are required to determine the optimal dose of IV acetaminophen to control rocuronium-induced withdrawal movement and suppress CGRP and PG E2 release.



Localization (release) of PG E2 associated with paracetamol, withdrawal and calcitonin gene-related peptide
2) Confidence 0.03 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2908220 Disease Relevance 0.29 Pain Relevance 1.33

General Comments

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