INT322533

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PIK3CB) signal transduction (PIK3CB) cell adhesion (PIK3CB)
nucleus (PIK3CB) cytoplasm (PIK3CB)
PIK3CB (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 78 91.00 High High
Apoptosis 27 61.96 Quite High
Cancer 105 38.44 Quite Low
Hyperplasia 6 5.00 Very Low Very Low Very Low
Metastasis 6 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Colon Cancer 6 5.00 Very Low Very Low Very Low
Retinoblastoma 3 5.00 Very Low Very Low Very Low
Lung Cancer 3 5.00 Very Low Very Low Very Low
Skin Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This increased expression of p27Kip1 correlates with decreased expression of p-PI3K, p-AKT, cyclin E, cyclin D1, cyclin D2 and increased expression of FOXO3a protein.
Negative_regulation (decreased) of Gene_expression (expression) of PI3K
1) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908539 Disease Relevance 0.28 Pain Relevance 0
As expected, the same treatments decreased the expression of phospho-PI3K and phospho-AKT; the total forms were unaffected.
Negative_regulation (decreased) of Gene_expression (expression) of PI3K
2) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908539 Disease Relevance 0 Pain Relevance 0
This increased expression of p27Kip1 correlates with decreased expression of p-PI3K, p-AKT, cyclin E, cyclin D1, cyclin D2 and increased expression of FOXO3a protein.
Negative_regulation (decreased) of Gene_expression (expression) of PI3K
3) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908539 Disease Relevance 0.29 Pain Relevance 0

General Comments

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