INT322536

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ctsb, Cdkn1b) endosome (Cdkn1b) mitochondrion (Ctsb)
protein complex (Cdkn1b) cytosol (Cdkn1b) extracellular space (Ctsb)
Ctsb (Mus musculus)
Cdkn1b (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 26 98.32 Very High Very High Very High
Apoptosis 9 69.28 Quite High
Cancer 35 45.76 Quite Low
Hyperplasia 2 7.36 Low Low
Metastasis 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Colon Cancer 2 5.00 Very Low Very Low Very Low
Retinoblastoma 1 5.00 Very Low Very Low Very Low
Lung Cancer 1 5.00 Very Low Very Low Very Low
Skin Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we show that shRNA-mediated downregulation of cathepsin B and uPAR results in G0/G1 arrest, prominent increased expression of p27Kip1 and inhibition of p-Rb.
Negative_regulation (downregulation) of cathepsin B Positive_regulation (results) of Gene_expression (expression) of p27Kip1
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908539 Disease Relevance 0.30 Pain Relevance 0

General Comments

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