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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.76
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DICER1) signal transduction (TNFSF10) extracellular space (TNFSF10)
extracellular region (TNFSF10) intracellular (DICER1) helicase activity (DICER1)
TNFSF10 (Homo sapiens)
DICER1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 75.72 Quite High
Inflammation 8 54.76 Quite High
cINOD 1 47.08 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 71 100.00 Very High Very High Very High
Death 10 100.00 Very High Very High Very High
Cancer 125 93.56 High High
Colon Cancer 44 83.48 Quite High
Solid Tumor 1 79.92 Quite High
INFLAMMATION 6 54.76 Quite High
Adenoma 1 50.52 Quite High
Inflammatory Bowel Disease 2 43.64 Quite Low
Toxicity 1 25.44 Quite Low
Familial Adenomatous Polyposis 1 14.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TRAIL initiates apoptosis by binding to two death receptors, DR4 and DR5, while binding to the decoy receptors which lack the death domain, such as DCR1, DCR2 and osteoprotegerin, inhibits its pro-apoptotic activity [9].
TRAIL Binding (binding) of DCR1 associated with apoptosis and death
1) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908545 Disease Relevance 1.76 Pain Relevance 0.07

General Comments

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