INT322588

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFSF10) extracellular space (TNFSF10) extracellular region (TNFSF10)
cell-cell signaling (TNFSF10)
Anatomy Link Frequency
Macrophages 2
TNFSF10 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 87.48 High High
Inflammation 8 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 71 93.76 High High
Colon Cancer 44 92.28 High High
Cancer 125 88.76 High High
Shock 2 85.92 High High
Acute Monocytic Leukemia 1 67.20 Quite High
Death 10 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Macrophages did not inhibit the expression of DR4 or DR5, or modulate the levels of decoy receptors DcR1 or DcR2 in HCT116/Hke-3 cells (Figure S1), suggesting that they do not modulate the responsiveness to TRAIL through regulation of TRAIL receptors.
Neg (not) Regulation (modulate) of Regulation (regulation) of TRAIL in Macrophages
1) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908545 Disease Relevance 0.79 Pain Relevance 0.04

General Comments

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