INT322621

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (TLR3) signal transduction (TLR3) endoplasmic reticulum (TLR3)
intracellular (TLR3) cytoplasm (TLR3)
TLR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 44.88 Quite Low
Potency 9 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Age-related Macular Degeneration 7 100.00 Very High Very High Very High
Myeloid Leukemia 1 74.32 Quite High
Pachyonychia Congenita 1 49.76 Quite Low
Congenital Anomalies 1 45.96 Quite Low
Hyperlipidemia 1 35.16 Quite Low
Asthma 1 18.80 Low Low
Respiratory Syncytial Virus 13 5.00 Very Low Very Low Very Low
Cancer 8 5.00 Very Low Very Low Very Low
Immunization 3 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AGN211745 too was shown to be possibly mediating its effects in preclinical models of AMD via TLR-3 activation [14].
Spec (possibly) Regulation (effects) of Positive_regulation (activation) of TLR-3 associated with age-related macular degeneration
1) Confidence 0.04 Published 2010 Journal Silence Section Body Doc Link PMC2908561 Disease Relevance 0.41 Pain Relevance 0

General Comments

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