INT322622

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SCPEP1) peptidase activity (SCPEP1) extracellular region (SCPEP1)
SCPEP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 9 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 3 72.36 Quite High
Hepatitis B Virus Infection 2 70.72 Quite High
Hepatitis 1 64.24 Quite High
Cancer 8 38.76 Quite Low
Respiratory Syncytial Virus 13 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 7 5.00 Very Low Very Low Very Low
Immunization 3 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent work with more sensitive quantitative PCR assays has clarified that in fact the drug is present (and presumably stabilized in RISC) at all time points when PD is observed after LNP-mediated siRNA delivery [21] (Alnylam Pharmaceuticals Inc., unpublished observations, Renta Hutabarat).
Localization (stabilized) of RISC
1) Confidence 0.07 Published 2010 Journal Silence Section Body Doc Link PMC2908561 Disease Relevance 0.27 Pain Relevance 0

General Comments

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