INT322667

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Vdac1) mitochondrion (Vdac1) nucleus (Pbrm1)
plasma membrane (Vdac1) DNA binding (Pbrm1) protein complex (Vdac1)
Anatomy Link Frequency
pore 1
Vdac1 (Mus musculus)
Pbrm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 13 65.28 Quite High
Inflammation 33 33.08 Quite Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 18 100.00 Very High Very High Very High
Targeted Disruption 2 97.36 Very High Very High Very High
Disease 8 82.28 Quite High
Death 40 78.00 Quite High
Stress 1 68.80 Quite High
Infection 19 67.16 Quite High
INFLAMMATION 42 64.88 Quite High
Influenza Virus Infection 26 50.00 Quite Low
Sprains And Strains 74 41.12 Quite Low
Influenza In Birds 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since its discovery the consensus has been that the PB1-F2 proteins from selected viruses are pro-apoptotic, targeting the mitochondria and inducing pore formation through association with VDAC1 and ANT3 [4], [11], [12], [19], [24].
VDAC1 Binding (association) of PB1 in pore associated with apoptosis
1) Confidence 0.15 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2908617 Disease Relevance 0.79 Pain Relevance 0.03

General Comments

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