INT322758

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TSC1) embryo development (TSC1) protein complex (TSC1)
cytoplasm (TSC1)
TSC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 3 10.32 Low Low
imagery 8 5.00 Very Low Very Low Very Low
Intractable pain 3 5.00 Very Low Very Low Very Low
pain flank 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 49 100.00 Very High Very High Very High
Myeloid Leukemia 27 100.00 Very High Very High Very High
Tuberous Sclerosis 5 100.00 Very High Very High Very High
Convulsion 3 100.00 Very High Very High Very High
Intellectual Impairment 3 100.00 Very High Very High Very High
Disease 3 100.00 Very High Very High Very High
Renal Cancer 10 98.68 Very High Very High Very High
Spontaneous Rupture 7 81.44 Quite High
Hemorrhage 3 10.32 Low Low
Malignant Neoplastic Disease 10 9.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Renal AMLs occupy 1-3% of renal tumors and occur in 2 clinical spectrums: sporadic and those associated with TSC.8 TSC is an autosomal disease entity with various characteristics such as mental retardation, adenoma sebaceum, seizure, renal manifestations, and loss of heterozygosity of TSC1 and TSC2 genes.4,9 Although AML is uncommon among the general population, previous studies has shown that 20% of patients with TSC are known to develop AML while on the other hand, more than 50% of AMLs are associated with TSC.7 In this rare setting, tumors tend to be larger, develop earlier in life, and are more often multiple or bilateral.3
Positive_regulation (with) of Localization (multiple) of TSC associated with myeloid leukemia, convulsion, intellectual impairment, cancer, tuberous sclerosis, renal cancer and disease
1) Confidence 0.06 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2908871 Disease Relevance 1.40 Pain Relevance 0

General Comments

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