INT322808

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.86
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MOCOS) extracellular space (RS1) small molecule metabolic process (MOCOS)
extracellular region (RS1) cell adhesion (RS1) cellular_component (MOCOS)
RS1 (Homo sapiens)
MOCOS (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 12 98.16 Very High Very High Very High
Glutamate 26 94.36 High High
Migraine 92 85.20 High High
Central nervous system 6 67.12 Quite High
Neurotransmitter 6 65.92 Quite High
Glutamate receptor 14 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
trigeminal ganglion 2 5.00 Very Low Very Low Very Low
central sensitization 2 5.00 Very Low Very Low Very Low
Thalamus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 12 98.16 Very High Very High Very High
Epilepsy 10 96.28 Very High Very High Very High
Headache 90 85.20 High High
Disease 10 5.00 Very Low Very Low Very Low
Migraine With Aura 6 5.00 Very Low Very Low Very Low
Shock 4 5.00 Very Low Very Low Very Low
Neuroblastoma 2 5.00 Very Low Very Low Very Low
Ganglion Cysts 2 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Two variants in the regulative regions of GRIA1 (rs2195450) and GRIA3 (rs3761555) genes resulted strongly associated with MA (P = 0.00002 and P = 0.0001, respectively), but not associated with MO, suggesting their role in cortical spreading depression.
rs2195450 Binding (associated) of MO associated with depression
1) Confidence 0.00 Published 2010 Journal BMC Med Genet Section Abstract Doc Link PMC2909201 Disease Relevance 0.43 Pain Relevance 0.51
Two variants in the regulative regions of GRIA1 (rs2195450) and GRIA3 (rs3761555) genes resulted strongly associated with MA (P = 0.00002 and P = 0.0001, respectively), but not associated with MO, suggesting their role in cortical spreading depression.
rs3761555 Binding (associated) of MO associated with depression
2) Confidence 0.00 Published 2010 Journal BMC Med Genet Section Abstract Doc Link PMC2909201 Disease Relevance 0.43 Pain Relevance 0.50

General Comments

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