INT322864

Context Info Confidence 0.63 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.76 Pain Relevance 0.09

cytosol (PDCD10) Golgi apparatus (PDCD10) plasma membrane (PDCD10) cytoplasm (PDCD10)

PDCD10 (Homo sapiens)

Pain Link Frequency Relevance Heat withdrawal 2 75.08 headache 2 54.44 imagery 4 44.16 Central nervous system 4 37.36 Glutamate 4 5.00

Disease Link Frequency Relevance Heat Apoptosis 18 99.68 Stress 2 92.56 Headache 2 54.44 Convulsion 2 53.60 Stroke 4 52.04 Aids-related Complex 2 36.96 Increased Venous Pressure Under Development 2 36.16 Metastasis 2 5.00 Congenital Anomalies 2 5.00 Adhesions 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Similar to earlier observations, PDCD10 was found to function in apoptotic pathways since overexpression of PDCD10 induces apoptosis through the caspase 3 pathway [26].

Positive_regulation (overexpression) of Gene_expression (overexpression) of PDCD10 associated with apoptosis

1) Confidence 0.63 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909203 Disease Relevance 0.76 Pain Relevance 0.09

COS7 cells were transfected with WT PDCD10-mCherry, ?

Positive_regulation (with) of Gene_expression (transfected) of PDCD10

2) Confidence 0.46 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909203 Disease Relevance 0 Pain Relevance 0

General Comments

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