INT322876

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.46 Pain Relevance 0.03

cytosol (PDCD10, Inpp5d) plasma membrane (PDCD10, Inpp5d) cytoplasm (PDCD10, Inpp5d) Golgi apparatus (PDCD10)

PDCD10 (Homo sapiens) Inpp5d (Mus musculus)

Pain Link Frequency Relevance Heat withdrawal 1 54.84 headache 1 34.20 Central nervous system 2 17.12 Glutamate 2 5.00 imagery 2 5.00

Disease Link Frequency Relevance Heat Apoptosis 9 81.44 Stress 1 72.32 Headache 1 34.20 Convulsion 1 33.36 Stroke 2 31.80 Increased Venous Pressure Under Development 1 15.92 Metastasis 1 5.00 Aids-related Complex 1 5.00 Congenital Anomalies 1 5.00 Adhesions 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We also showed that PDCD10 binds to both phosphatidylinositol bis- or tris-phosphates, but seems to have the highest affinity to phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) [28].

PDCD10 Binding (affinity) of phosphatidylinositol-3,4,5-trisphosphate

1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909203 Disease Relevance 0.46 Pain Relevance 0.03

General Comments

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