INT322896

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (SPARC) extracellular space (SPARC) extracellular region (SPARC)
proteinaceous extracellular matrix (SPARC) nucleus (SPARC) intracellular (SPARC)
Anatomy Link Frequency
chondrocytes 2
osteoblasts 1
SPARC (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 10 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 70 80.60 Quite High
Death 10 49.76 Quite Low
Hypertrophy 20 45.04 Quite Low
Stress 5 11.52 Low Low
Congenital Anomalies 90 5.00 Very Low Very Low Very Low
Intervertebral Disk Degeneration 40 5.00 Very Low Very Low Very Low
Calcification 15 5.00 Very Low Very Low Very Low
Apoptosis 15 5.00 Very Low Very Low Very Low
Hypercalcemia 10 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During the fusion process a metaplastic shift appeared in the arch centra where cells in the intermediate zone between osteoblasts and chondrocytes co-transcribed col1a, col2a, runx2, osteocalcin and osteonectin, as visualized by ISH.
Transcription (transcribed) of osteonectin in chondrocytes
1) Confidence 0.20 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2909226 Disease Relevance 0.22 Pain Relevance 0
Transcription of osteonectin was also associated with chondrocytes in regions where arch centra fused (Figure 6K, L).
Transcription (Transcription) of osteonectin in chondrocytes
2) Confidence 0.20 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2909226 Disease Relevance 0 Pain Relevance 0
Strong osteonectin transcription correlated with an up-regulated mRNA transcription observed from qPCR.
Transcription (transcription) of osteonectin
3) Confidence 0.17 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2909226 Disease Relevance 0 Pain Relevance 0
Strong osteonectin transcription correlated with an up-regulated mRNA transcription observed from qPCR.
Transcription (transcription) of osteonectin
4) Confidence 0.13 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2909226 Disease Relevance 0 Pain Relevance 0
During the fusion process a metaplastic shift appeared in the arch centra where cells in the intermediate zone between osteoblasts and chondrocytes co-transcribed col1a, col2a, runx2, osteocalcin and osteonectin, as visualized by ISH.
Transcription (transcribed) of osteonectin in osteoblasts
5) Confidence 0.07 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2909226 Disease Relevance 0.22 Pain Relevance 0

General Comments

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