INT323077

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.57
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger2) mitochondrion (CPOX) small molecule metabolic process (CPOX)
oxidoreductase activity (CPOX) plasma membrane (Ptger2) signal transducer activity (Ptger2)
Anatomy Link Frequency
PGE2 2
CPOX (Homo sapiens)
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 7 99.22 Very High Very High Very High
Pain 4 99.12 Very High Very High Very High
Inflammation 28 97.36 Very High Very High Very High
Osteoarthritis 1 94.24 High High
rheumatoid arthritis 1 93.48 High High
Hyperalgesia 1 89.88 High High
COX-2 inhibitor 4 77.12 Quite High
Inflammatory response 5 19.52 Low Low
cytokine 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 4 99.12 Very High Very High Very High
INFLAMMATION 33 98.94 Very High Very High Very High
Dermatitis 2 95.96 Very High Very High Very High
Osteoarthritis 1 94.24 High High
Rheumatoid Arthritis 1 93.48 High High
Disease 6 92.28 High High
Hyperalgesia 1 89.88 High High
Pressure And Volume Under Development 1 89.20 High High
Wound Healing 34 76.80 Quite High
Keloid Scars 50 53.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conventionally, nonsteroidal anti-inflammatory drugs (NSAIDs) or their selective cyclooxygenase-2 (COX-2) inhibitors are reported to inhibit PGE2 production and act as effective pain-killers, since they are able to reduce inflammation successfully [3, 4].
COX Negative_regulation (inhibit) of Gene_expression (production) of PGE2 in PGE2 associated with pain, inflammation and cinod
1) Confidence 0.00 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2910481 Disease Relevance 1.57 Pain Relevance 1.05

General Comments

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