INT323141

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.06
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL10) extracellular region (IL10) intracellular (IL10)
cell-cell signaling (IL10) response to stress (IL10)
IL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 64 100.00 Very High Very High Very High
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Recurrence 42 99.42 Very High Very High Very High
Disease Progression 2 96.20 Very High Very High Very High
Leishmaniasis 66 79.04 Quite High
Disease 20 56.60 Quite High
Infection 2 24.56 Low Low
Body Weight 10 5.00 Very Low Very Low Very Low
Fever 6 5.00 Very Low Very Low Very Low
Anaemia 2 5.00 Very Low Very Low Very Low
Weight Loss 2 5.00 Very Low Very Low Very Low
Nephrotoxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients who suffered relapse, showed neither significant elevation of Th1 cytokines nor downregulation of IL-10, at this time point, although TGF-?
Neg (neither) Positive_regulation (elevation) of Negative_regulation (downregulation) of IL-10 associated with recurrence and cytokine
1) Confidence 0.37 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2910702 Disease Relevance 0.57 Pain Relevance 0.22
This differential immune response 1 week posttreatment between the responder and non-responder patients further substantiates the significance of upregulation of Th1 cytokines and simultaneous downregulation of IL-10 for the success of therapy.
Positive_regulation (upregulation) of Negative_regulation (downregulation) of IL-10 associated with cytokine
2) Confidence 0.27 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2910702 Disease Relevance 0.49 Pain Relevance 0.22

General Comments

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