INT323175

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme binding (PRKCA, Akt1) cytoplasm (PRKCA, Akt1) cytosol (PRKCA, Akt1)
signal transduction (PRKCA, Akt1) nucleus (PRKCA, Akt1) plasma membrane (PRKCA, Akt1)
PRKCA (Homo sapiens)
Akt1 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 24 100.00 Very High Very High Very High
agonist 76 97.04 Very High Very High Very High
Calcium channel 28 92.64 High High
GABAergic 12 17.28 Low Low
tetrodotoxin 16 5.00 Very Low Very Low Very Low
imagery 14 5.00 Very Low Very Low Very Low
Serotonin 8 5.00 Very Low Very Low Very Low
gABA 6 5.00 Very Low Very Low Very Low
Neurotransmitter 6 5.00 Very Low Very Low Very Low
Glutamate 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hot Flashes 20 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low
Breast Cancer 8 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 8 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low
Reprotox - General 3 4 5.00 Very Low Very Low Very Low
Endometriosis (extended) 4 5.00 Very Low Very Low Very Low
Uterine Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PKC stimulates the ERK/MAPK and AKT pathway by phosphorylating and activating Raf-1 and AKT [85].
PKC Positive_regulation (stimulates) of AKT associated with kinase c
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910705 Disease Relevance 0 Pain Relevance 0.54
PKC stimulates the ERK/MAPK and AKT pathway by phosphorylating and activating Raf-1 and AKT [85].
PKC Positive_regulation (activating) of AKT associated with kinase c
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910705 Disease Relevance 0 Pain Relevance 0.56

General Comments

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