INT323197

Context Info Confidence 0.06 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0

mitochondrion (POLRMT) DNA binding (POLRMT) nucleotidyltransferase activity (POLRMT)

POLRMT (Homo sapiens)

Pain Link Frequency Relevance Heat ischemia 3 5.00 Inflammation 3 5.00 cINOD 1 5.00 Crohn's disease 1 5.00 Inflammatory response 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Stress 20 73.52 Apoptosis 12 35.12 Death 3 29.36 Inflammatory Bowel Disease 7 5.00 Parkinson's Disease 6 5.00 INFLAMMATION 3 5.00 Cv Unclassified Under Development 3 5.00 Disease 3 5.00 Injury 2 5.00 Reperfusion Injury 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Human mitochondrial transcription requires bacteriophage-related RNA polymerase, POLRMT, mtDNA-binding protein, h-mtTFA/TFAM, and two transcription factors/rRNA methyltransferases, h-mtTFB1 and h-mtTFB2.

Positive_regulation (requires) of POLRMT

1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910735 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.