INT323203

Context Info Confidence 0.07 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0

mitochondrion (POLRMT) DNA binding (POLRMT) nucleotidyltransferase activity (POLRMT)

Anatomy Link Frequency Caco-2 1 POLRMT (Homo sapiens)

Pain Link Frequency Relevance Heat ischemia 3 5.00 Inflammation 3 5.00 cINOD 1 5.00 Crohn's disease 1 5.00 Inflammatory response 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Stress 20 90.12 Apoptosis 12 44.48 Inflammatory Bowel Disease 7 5.00 Parkinson's Disease 6 5.00 Death 3 5.00 INFLAMMATION 3 5.00 Cv Unclassified Under Development 3 5.00 Disease 3 5.00 Injury 2 5.00 Reperfusion Injury 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

PCR and Western Blot analyses showed a significant (P<0.01) increase in mtTFA, mtTFB1 and mtTFB2 gene expression (Figure 9A) and protein mass (Figure 9B) without any changes in POLRMT in Caco-2/15 cells treated with FE/ASC compared with controls.

Neg (without) Regulation (changes) of POLRMT in Caco-2

1) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910735 Disease Relevance 0.16 Pain Relevance 0

General Comments

This test has worked.