INT323258

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Dhfr) mRNA binding (Dhfr)
Dhfr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Tetrahydrobiopterin 21 99.66 Very High Very High Very High
Bioavailability 4 30.52 Quite Low
potassium channel 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
cOX1 2 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
TRP channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 2 87.32 High High
Hyperlipidemia 2 86.48 High High
Diabetes Mellitus 7 85.60 High High
Hypertension 45 85.20 High High
Nicotine Addiction 1 83.80 Quite High
Increased Venous Pressure Under Development 14 83.20 Quite High
Atherosclerosis 1 75.68 Quite High
Cardiovascular Disease 9 30.80 Quite Low
Stress 4 21.68 Low Low
Atherosclerotic Plaque 1 6.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alternative strategies include supplementation with folic acid, which enhances the binding affinity of BH4 to NOS, stabilizes BH4 chemically, and stimulates DHFR.
Positive_regulation (stimulates) of DHFR associated with tetrahydrobiopterin
1) Confidence 0.20 Published 2010 Journal Curr Hypertens Rep Section Body Doc Link PMC2910890 Disease Relevance 0.66 Pain Relevance 0.49

General Comments

This test has worked.

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