INT323286

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (CYP4A11, Kcnma1) transport (Kcnma1) small molecule metabolic process (CYP4A11)
plasma membrane (Kcnma1) transmembrane transport (Kcnma1)
Anatomy Link Frequency
smooth muscle cells 1
CYP4A11 (Homo sapiens)
Kcnma1 (Mus musculus)
Pain Link Frequency Relevance Heat
potassium channel 4 74.28 Quite High
Inflammatory response 2 18.40 Low Low
Tetrahydrobiopterin 21 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
cOX1 2 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
TRP channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 14 100.00 Very High Very High Very High
Hypotension 2 67.76 Quite High
Hypertension 45 59.76 Quite High
Stroke 1 50.56 Quite High
Diabetes Mellitus 7 34.00 Quite Low
Cardiovascular Disease 9 30.80 Quite Low
INFLAMMATION 2 18.40 Low Low
Stress 4 5.00 Very Low Very Low Very Low
Coronary Heart Disease 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 12-LO product, 12(S)-HETE, produces vasodilatation by activating BKCa channels and thus hyperpolarizing the vascular smooth muscle cells, whereas HEETA and THETA, generated by 15-LO, open SKCa-like channels [30•].
HETE Positive_regulation (activating) of BKCa in smooth muscle cells associated with increased venous pressure under development
1) Confidence 0.01 Published 2010 Journal Curr Hypertens Rep Section Body Doc Link PMC2910890 Disease Relevance 0.45 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox