INT323314

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.11
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (HTT) endoplasmic reticulum (HTT) protein complex (HTT)
cytoplasm (HTT) cytosol (HTT) cell death (HTT)
Anatomy Link Frequency
motoneuron 1
HTT (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 81.80 Quite High
Inflammation 8 80.44 Quite High
member 8 4 75.68 Quite High
Central nervous system 80 47.96 Quite Low
Neuropeptide 12 5.00 Very Low Very Low Very Low
withdrawal 8 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
interneuron 4 5.00 Very Low Very Low Very Low
nMDA receptor 4 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 44 99.56 Very High Very High Very High
Death 4 90.40 High High
Stress 8 89.28 High High
Necrosis 8 82.60 Quite High
Cancer 8 82.24 Quite High
INFLAMMATION 8 80.44 Quite High
Aging 312 54.72 Quite High
Apoptosis 32 34.20 Quite Low
Alzheimer's Dementia 20 5.00 Very Low Very Low Very Low
Ganglion Cysts 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also notable transcripts showing high differential expression in old R2 are Huntington's disease related transcripts (including huntingtin and huntingtin-interacting protein, and huntingtin associated transcripts).
Transcription (including) of huntingtin associated with disease
1) Confidence 0.04 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2910937 Disease Relevance 0.69 Pain Relevance 0.16
Also notable transcripts showing high differential expression in old R2 are Huntington's disease related transcripts (including huntingtin and huntingtin-interacting protein, and huntingtin associated transcripts).
Transcription (including) of huntingtin associated with disease
2) Confidence 0.04 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2910937 Disease Relevance 0.68 Pain Relevance 0.16
Also notable transcripts showing high differential expression in old R2 are Huntington's disease related transcripts (including huntingtin and huntingtin-interacting protein, and huntingtin associated transcripts).
Transcription (including) of huntingtin associated with disease
3) Confidence 0.04 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2910937 Disease Relevance 0.68 Pain Relevance 0.16
High abundance of antisense transcripts for ApoE receptor and huntingtin were found in the L7 motoneuron but not other tested cells.
Transcription (transcripts) of huntingtin in motoneuron
4) Confidence 0.03 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2910937 Disease Relevance 0.06 Pain Relevance 0

General Comments

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