INT323462

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Context Info
Confidence 0.27
First Reported 2010
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl) extracellular region (Ghrl) cytoplasm (Ghrl)
Anatomy Link Frequency
posterior 2
Ghrl (Mus musculus)
Pain Link Frequency Relevance Heat
Ventral tegmentum 68 100.00 Very High Very High Very High
nMDA receptor antagonist 3 100.00 Very High Very High Very High
Somatostatin 4 99.28 Very High Very High Very High
Dopamine 73 97.84 Very High Very High Very High
antagonist 58 96.88 Very High Very High Very High
opioid receptor 8 96.44 Very High Very High Very High
vagus nerve 2 45.76 Quite Low
Eae 18 20.56 Low Low
tolerance 18 5.00 Very Low Very Low Very Low
Opioid 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 18 86.72 High High
Impaired Glucose Tolerance 20 37.52 Quite Low
Obesity 50 36.40 Quite Low
Hyperglycemia 4 22.04 Low Low
Diabetes Mellitus 30 14.96 Low Low
Disease 6 14.12 Low Low
Appetite Loss 5 5.64 Low Low
Targeted Disruption 54 5.00 Very Low Very Low Very Low
Body Weight 11 5.00 Very Low Very Low Very Low
Hyperinsulinism 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of intra-VTA administration of a NMDA receptor antagonist on ghrelin-induced locomotor stimulation and increased accumbal dopamine release in mice
Regulation (Effects) of Gene_expression (administration) of ghrelin associated with ventral tegmentum, dopamine and nmda receptor antagonist
1) Confidence 0.27 Published 2011 Journal Addiction Biology Section Body Doc Link PMC3015055 Disease Relevance 0 Pain Relevance 0.91
In a posterior work the same investigators studied, for the first time, the concomitant effects of exogenous ghrelin and a pancreatic clamp on glucose metabolism in humans; they used a prolonged ghrelin infusion in addition to a somatostatin infusion to avoid GH secretion.
Regulation (prolonged) of Gene_expression (infusion) of ghrelin in posterior associated with somatostatin
2) Confidence 0.19 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2911604 Disease Relevance 0.15 Pain Relevance 0.08

General Comments

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