INT323485

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.99
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl, Ins1) extracellular region (Ghrl, Ins1) cytoplasm (Ghrl, Ins1)
carbohydrate metabolic process (Ins1)
Anatomy Link Frequency
blood 2
Ghrl (Mus musculus)
Ins1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 18 98.44 Very High Very High Very High
antagonist 14 5.00 Very Low Very Low Very Low
Somatostatin 4 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
vagus nerve 2 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Action potential 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Impaired Glucose Tolerance 20 98.76 Very High Very High Very High
Targeted Disruption 54 96.84 Very High Very High Very High
Obesity 49 96.60 Very High Very High Very High
Hyperinsulinism 10 91.76 High High
Body Weight Changes 1 27.40 Quite Low
Diabetes Mellitus 30 5.00 Very Low Very Low Very Low
Insulin Resistance 18 5.00 Very Low Very Low Very Low
Body Weight 9 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Appetite Loss 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When ghrelin KO mice, maintained from weaning on regular chow, were subjected to IP-GTT, ghrelin treatment produced higher blood glucose and markedly lowers insulin levels, showing that ghrelin acutely suppresses insulin release, suggesting that the improved glucose tolerance which was observed in ghrelin KO ob/ob mice fed with HFD during IP-GTT could be a consequence of ghrelin-ablation.
ghrelin Negative_regulation (suppresses) of Localization (release) of insulin in blood associated with targeted disruption, obesity, tolerance and impaired glucose tolerance
1) Confidence 0.15 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2911604 Disease Relevance 1.99 Pain Relevance 0.05

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox