INT32353

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Context Info
Confidence 0.52
First Reported 1980
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 1.37
Pain Relevance 3.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Lct) carbohydrate metabolic process (Lct)
Anatomy Link Frequency
hypothalamus 1
jejunum 1
BBM 1
NIL 1
Lct (Rattus norvegicus)
Pain Link Frequency Relevance Heat
analgesia 4 98.64 Very High Very High Very High
Glutamate 9 98.54 Very High Very High Very High
Pain 2 92.92 High High
aspirin 6 92.68 High High
agonist 2 87.44 High High
Clonidine 10 86.72 High High
opiate 2 84.48 Quite High
antagonist 3 83.92 Quite High
cINOD 8 82.72 Quite High
Dopamine 2 78.08 Quite High
Disease Link Frequency Relevance Heat
Body Weight 4 95.40 Very High Very High Very High
Pain 2 92.92 High High
Shock 1 86.56 High High
INFLAMMATION 4 82.16 Quite High
Stress 2 78.56 Quite High
Toxicity 1 78.00 Quite High
Death 1 75.32 Quite High
Convulsion 1 74.92 Quite High
Diarrhoea 1 74.52 Quite High
Abdominal Pain 1 74.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lactase levels were affected in a variable manner.
Regulation (affected) of Lactase
1) Confidence 0.52 Published 1994 Journal Gastroenterol. Clin. Biol. Section Abstract Doc Link 7958644 Disease Relevance 0.38 Pain Relevance 0.07
The C-terminus of beta-endorphin (beta-LPH 78-91) was ineffective. alpha-Endorphin facilitated inhibitory avoidance behavior in a dose dependent manner.
Regulation (ineffective) of LPH
2) Confidence 0.44 Published 1983 Journal Psychoneuroendocrinology Section Abstract Doc Link 6201940 Disease Relevance 0 Pain Relevance 0.25
At the end of 28 days of treatment, membranes were isolated from different intestinal segments of all the groups and changes in BBM-associated enzymes such as sucrase, lactase, maltase, alkaline phosphatase and the transport properties of D-glucose and its kinetics were studied.
Regulation (changes) of lactase in BBM
3) Confidence 0.30 Published 2005 Journal Pharmacol Rep Section Abstract Doc Link 16382204 Disease Relevance 0.16 Pain Relevance 0.39
Gel chromatography indicated that alterations in IR-BE in the AP corresponded to similar changes in beta-endorphin (BE) and beta-lipotropin (LPH) and that BE alone comprised the immunoreactivity detected in the NIL and hypothalamus regardless of treatment.
Regulation (changes) of LPH in hypothalamus
4) Confidence 0.26 Published 1986 Journal Peptides Section Abstract Doc Link 2948165 Disease Relevance 0 Pain Relevance 0.57
After six weeks of treatment, brush border membrane was isolated from the jejunum segment of all the groups and changes in the associated enzymes such as sucrase, lactase, maltase, alkaline phosphatase, membrane lipid composition, fluorescence polarizations of diphenylhexatriene, pyrene excimer formation, histological changes and surface characteristics were studied.
Regulation (changes) of lactase in jejunum
5) Confidence 0.17 Published 2008 Journal Nutr Hosp Section Abstract Doc Link 19160894 Disease Relevance 0.52 Pain Relevance 0.34
The present study examined whether MSG-treated rats, as compared to littermate controls, exhibited concomitant changes in the immunocytochemical distribution of ACTH and beta-LPH, and their reactivity to several analgesia-inducing manipulations.
Regulation (changes) of beta-LPH associated with glutamate and analgesia
6) Confidence 0.13 Published 1980 Journal Neuroendocrinology Section Abstract Doc Link 6247667 Disease Relevance 0.32 Pain Relevance 0.97
Gel chromatography indicated that alterations in IR-BE in the AP corresponded to similar changes in beta-endorphin (BE) and beta-lipotropin (LPH) and that BE alone comprised the immunoreactivity detected in the NIL and hypothalamus regardless of treatment.
Regulation (changes) of LPH in NIL
7) Confidence 0.09 Published 1986 Journal Peptides Section Abstract Doc Link 2948165 Disease Relevance 0 Pain Relevance 0.57

General Comments

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