INT323710

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.55
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TRAF6) signal transduction (TRAF6) nucleolus (TRAF6)
plasma membrane (TRAF6) nucleus (TRAF6) ligase activity (TRAF6)
Anatomy Link Frequency
macrophages 1
TRAF6 (Homo sapiens)
MIR146A (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 56 93.52 High High
cytokine 12 66.08 Quite High
psoriasis 2 57.72 Quite High
Inflammation 13 43.88 Quite Low
corticosteroid 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 56 93.52 High High
Systemic Lupus Erythematosus 2 61.84 Quite High
Psoriasis 2 57.72 Quite High
Arthritis 2 43.88 Quite Low
INFLAMMATION 13 37.76 Quite Low
Repression 3 15.12 Low Low
Disease 9 14.72 Low Low
Apoptosis 24 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Autoimmune Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TRAF6, a known target of miR-146a in macrophages and PBMCs, plays a key role in mediating signals from TNF receptor and IL-1 receptor in innate immunity.
TRAF6 Regulation (target) of miR-146a in macrophages
1) Confidence 0.06 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911863 Disease Relevance 0.55 Pain Relevance 0.28

General Comments

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