INT323752

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.36
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (FASLG) extracellular space (FASLG) extracellular region (FASLG)
plasma membrane (FASLG) cell-cell signaling (FASLG)
Anatomy Link Frequency
T cells 1
FASLG (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 56 99.40 Very High Very High Very High
rheumatoid arthritis 60 83.36 Quite High
Inflammation 18 70.76 Quite High
cytokine 12 53.28 Quite High
Rheumatism 1 37.60 Quite Low
cINOD 3 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 34 100.00 Very High Very High Very High
Autoimmune Disease 14 99.40 Very High Very High Very High
Arthritis 4 99.40 Very High Very High Very High
Death 17 91.88 High High
Genetic Predisposition To Disease 1 88.96 High High
Rheumatoid Arthritis 113 83.36 Quite High
Disease 20 71.08 Quite High
INFLAMMATION 19 70.76 Quite High
Autoimmune Lymphoproliferative Syndrome 1 68.72 Quite High
Rheumatic Diseases 1 37.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These T cells are unusually resistant to apoptosis in SF that contains a significant amount of pro-apoptotic factors such as bioactive FasL, TRAIL and TNF-?
Negative_regulation (amount) of FasL in T cells associated with apoptosis
1) Confidence 0.18 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911863 Disease Relevance 1.12 Pain Relevance 0.29
Like CD95L, TRAIL has been reported to be a potent inhibitor of autoimmune arthritis [24].
Negative_regulation (inhibitor) of CD95L associated with arthritis
2) Confidence 0.08 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2936350 Disease Relevance 1.24 Pain Relevance 0.14

General Comments

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