INT323757

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.73
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (ACE2, ANG) extracellular region (ACE2, ANG) cell differentiation (ANG)
DNA binding (ANG) peptidase activity (ACE2) cell death (ANG)
ACE2 (Homo sapiens)
ANG (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 3 85.52 High High
ischemia 18 70.68 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 7 97.64 Very High Very High Very High
Disease 29 96.16 Very High Very High Very High
Pulmonary Hypertension 31 78.64 Quite High
Cv Unclassified Under Development 18 70.68 Quite High
Systemic Lupus Erythematosus 24 67.24 Quite High
Systemic Sclerosis 28 66.36 Quite High
Congenital Anomalies 2 60.36 Quite High
Necrosis 7 5.00 Very Low Very Low Very Low
Myocardial Infarction 3 5.00 Very Low Very Low Very Low
Pancytopenia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The inhibition of ACE2 by autoantibodies may result in reduced physiological levels of the vasoprotective agent Ang(1-7) in the local vascular milieu, which may induce vasculopathies in patients with underlying disease such as CTD.
Negative_regulation (inhibition) of ACE2 Negative_regulation (reduced) of Ang associated with disease
1) Confidence 0.18 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911869 Disease Relevance 1.73 Pain Relevance 0.17

General Comments

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