INT323762

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 3
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.63
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (ACE2) extracellular space (ACE2) extracellular region (ACE2)
plasma membrane (ACE2)
ACE2 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 54 85.60 High High
Pain 3 22.72 Low Low
antagonist 9 17.16 Low Low
anesthesia 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 87 95.84 Very High Very High Very High
Pulmonary Hypertension 93 87.68 High High
Cv Unclassified Under Development 54 85.60 High High
Systemic Lupus Erythematosus 72 56.72 Quite High
Fever 6 56.00 Quite High
Pancytopenia 6 55.44 Quite High
Necrosis 21 52.40 Quite High
Systemic Sclerosis 84 46.80 Quite Low
Hypertension 21 44.00 Quite Low
Myocardial Infarction 9 42.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of each IgG on the activity of recombinant human ACE2 (standard rACE2; R&D Systems) was examined as described.


Spec (examined) Regulation (effect) of rACE2
1) Confidence 0.39 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911869 Disease Relevance 0.72 Pain Relevance 0.04
The effect of each IgG on the activity of recombinant human ACE2 (standard rACE2; R&D Systems) was examined as described.


Spec (examined) Regulation (effect) of ACE2
2) Confidence 0.39 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911869 Disease Relevance 0.70 Pain Relevance 0.04
First, the RFU value of the ACE2 enzyme activity, which was blocked by DX600 (Additional file 1), was determined in 18 patients with vasculopathy, in 16 control patients without vasculopathy, and in 26 healthy subjects.
Spec (determined) Regulation (value) of ACE2
3) Confidence 0.27 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911869 Disease Relevance 0.21 Pain Relevance 0.04

General Comments

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