INT323765

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lep) extracellular space (Lep) extracellular region (Lep)
intracellular (Lep) lipid metabolic process (Lep)
Lep (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 55 100.00 Very High Very High Very High
Pain 6 96.68 Very High Very High Very High
Inflammation 5 85.68 High High
imagery 2 74.68 Quite High
cytokine 3 71.20 Quite High
metalloproteinase 3 26.32 Quite Low
rheumatoid arthritis 5 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 55 100.00 Very High Very High Very High
Pain 6 96.68 Very High Very High Very High
INFLAMMATION 6 85.68 High High
Synovitis 1 78.40 Quite High
Cancer 2 68.80 Quite High
Necrosis 2 68.32 Quite High
Obesity 43 56.72 Quite High
Osteophyte 10 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Nicotine Addiction 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our results, it is not surprising that the association between OA and leptin decreased somewhat in magnitude after adjustment for IL-6, because leptin belongs structurally to the IL-6 family, and their serum levels were weakly related to each other in this sample.
Negative_regulation (decreased) of leptin Binding (association) of associated with osteoarthritis
1) Confidence 0.37 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911879 Disease Relevance 0.91 Pain Relevance 0.42

General Comments

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