INT323773

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.54
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6, Lep) extracellular region (Il6, Lep) signal transduction (Lep)
intracellular (Lep) lipid metabolic process (Lep)
Anatomy Link Frequency
fat 2
Il6 (Mus musculus)
Lep (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 165 99.64 Very High Very High Very High
Pain 18 99.00 Very High Very High Very High
rheumatoid arthritis 15 85.12 High High
addiction 3 22.64 Low Low
metalloproteinase 9 6.36 Low Low
Inflammation 15 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 165 99.64 Very High Very High Very High
Pain 18 99.00 Very High Very High Very High
Cardiovascular Disease 12 98.44 Very High Very High Very High
Obesity 129 98.32 Very High Very High Very High
Nicotine Addiction 15 98.12 Very High Very High Very High
Disease 27 97.28 Very High Very High Very High
Asthma 12 95.84 Very High Very High Very High
Osteophyte 30 86.16 High High
Diabetes Mellitus 12 85.64 High High
Rheumatoid Arthritis 15 85.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-6 was weakly associated with leptin and also associated with trunk and total fat ratios in our data, but did not mediate the effect of any of these fat measures on JSN.
IL-6 Binding (associated) of leptin in fat
1) Confidence 0.29 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911879 Disease Relevance 1.08 Pain Relevance 0.23
IL-6 was weakly associated with leptin and also associated with trunk and total fat ratios in our data, but did not mediate the effect of any of these fat measures on JSN.
IL-6 Binding (associated) of leptin in fat
2) Confidence 0.21 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911879 Disease Relevance 1.08 Pain Relevance 0.23
A significant positive association between IL-6 and leptin was found after adjustment for age, sex, BMI, smoking history, and disease status (r = 0.16; P = 0.032), although this association became nonsignificant when either sex group was analyzed.
IL-6 Binding (association) of leptin associated with nicotine addiction, obesity and disease
3) Confidence 0.21 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911879 Disease Relevance 1.38 Pain Relevance 0.14

General Comments

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