INT323786

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.43 Pain Relevance 0.14

nucleolus (PQBP1) nucleus (PQBP1) DNA binding (PQBP1) cytoplasm (PQBP1)

Anatomy Link Frequency joint 1 PQBP1 (Homo sapiens)

Pain Link Frequency Relevance Heat headache 3 81.72 Inflammation 36 61.84 imagery 1 49.08 Pain 1 39.68 visual analogue scale 5 37.52 corticosteroid 10 23.92 rheumatoid arthritis 31 5.00 Crohn's disease 20 5.00 methotrexate 7 5.00 cytokine 6 5.00

Disease Link Frequency Relevance Heat Fatigue 2 84.24 Headache 3 81.72 Inflammatory Bowel Disease 51 80.40 Recurrence 7 72.56 INFLAMMATION 33 61.84 Obesity 7 48.32 Disease 55 45.52 Pain 1 39.68 Rheumatoid Arthritis 31 5.00 Osteoporosis 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Progressive joint damage in the first year was defined as an increase in total SHS of 5 units or more at year one compared with baseline.

Positive_regulation (increase) of SHS in joint

1) Confidence 0.03 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0 Pain Relevance 0

However, the dimensions "worry" and to a lesser extent even "general well being" in SHS increased assessed between the later time points measured.

Positive_regulation (increased) of SHS

2) Confidence 0.01 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2914086 Disease Relevance 0.43 Pain Relevance 0.14

General Comments

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