INT323806

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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NFAT5) extracellular region (ACAN) cell adhesion (ACAN)
proteinaceous extracellular matrix (ACAN) nucleus (NFAT5) DNA binding (NFAT5)
NFAT5 (Homo sapiens)
ACAN (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 29 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 1 67.60 Quite High
Stress 7 47.40 Quite Low
Osteoarthritis 33 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Infection 1 5.00 Very Low Very Low Very Low
Amputation 1 5.00 Very Low Very Low Very Low
Arthralgia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, while high NaCl rapidly activates p38 MAPK, its action can be isoform specific and may exert opposing effects on NFAT5 [85], which in turn may influence COL2A1 and AGC1 transcription differently in a tonicity-dependent manner.
NFAT5 Spec (may) Regulation (influence) of Transcription (transcription) of AGC1
1) Confidence 0.40 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911888 Disease Relevance 0.07 Pain Relevance 0

General Comments

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