INT323872

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LEP, IGF1) extracellular region (LEP, IGF1) signal transduction (IGF1)
lipid metabolic process (LEP)
LEP (Homo sapiens)
IGF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 54 76.00 Quite High
Inflammation 6 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 104 87.32 High High
Overweight 13 86.24 High High
Osteoarthritis 54 76.00 Quite High
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low
Starvation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By contrast, leptin induced the expression of IGF-1 with a pattern of response similar to that found for type 2 collagen.
leptin Positive_regulation (induced) of Gene_expression (expression) of IGF-1
1) Confidence 0.35 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911905 Disease Relevance 0.77 Pain Relevance 0.07

General Comments

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