INT323878

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LEP, MMP13) extracellular region (LEP, MMP13) peptidase activity (MMP13)
Golgi apparatus (MMP13) proteinaceous extracellular matrix (MMP13) lysosome (MMP13)
Anatomy Link Frequency
chondrocytes 1
LEP (Homo sapiens)
MMP13 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 54 91.44 High High
Inflammatory mediators 2 36.00 Quite Low
Inflammation 6 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Overweight 13 98.24 Very High Very High Very High
Osteoarthritis 54 91.44 High High
Obesity 104 91.32 High High
INFLAMMATION 7 36.00 Quite Low
Body Weight 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low
Starvation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The gene encoding MMP-13 was not identified as a significant target of leptin for chondrocytes originated from normal or overweight patients.
leptin Binding (target) of MMP-13 in chondrocytes associated with overweight
1) Confidence 0.17 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911905 Disease Relevance 0.77 Pain Relevance 0.05

General Comments

This test has worked.

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