INT323885

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (NOS2) cytoplasm (NOS2) lipid metabolic process (LEP)
cytosol (NOS2) extracellular space (LEP) extracellular region (LEP)
Anatomy Link Frequency
chondrocytes 2
LEP (Homo sapiens)
NOS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 54 91.36 High High
Inflammatory mediators 2 87.36 High High
cytokine 1 82.80 Quite High
Inflammation 6 70.84 Quite High
metalloproteinase 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 54 91.36 High High
INFLAMMATION 7 86.96 High High
Obesity 104 74.68 Quite High
Arthritis 1 70.84 Quite High
Overweight 13 16.40 Low Low
Body Weight 2 11.28 Low Low
Pain 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low
Starvation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The use of cartilage explants instead of isolated chondrocytes may explain the discrepancies because other authors were unable to find any effect of leptin on the expression of iNOS in cultured human primary chondrocytes [9,14].
leptin Regulation (effect) of Gene_expression (expression) of iNOS in chondrocytes
1) Confidence 0.26 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911905 Disease Relevance 1.07 Pain Relevance 0.35

General Comments

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