INT323896

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.25
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (SOAT1) transferase activity, transferring acyl groups (SOAT1)
Anatomy Link Frequency
chondrocytes 2
SOAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 30 95.52 Very High Very High Very High
Osteoarthritis 54 87.20 High High
Inflammation 27 50.00 Quite Low
Inflammatory mediators 2 29.40 Quite Low
Arthritis 48 5.00 Very Low Very Low Very Low
Potency 26 5.00 Very Low Very Low Very Low
rheumatoid arthritis 22 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
psoriasis 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 104 93.68 High High
Osteoarthritis 54 87.20 High High
Body Weight 2 68.56 Quite High
Overweight 13 62.92 Quite High
INFLAMMATION 27 50.00 Quite Low
Arthritis 53 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 22 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Immunization 9 5.00 Very Low Very Low Very Low
Hematological Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By contrast, the phosphorylation of STAT 5A and 5B in leptin-stimulated chondrocytes remained unchanged compared with untreated cells (data not shown).
Neg (unchanged) Regulation (unchanged) of Phosphorylation (phosphorylation) of STAT in chondrocytes
1) Confidence 0.14 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911905 Disease Relevance 1.25 Pain Relevance 0.13
Percent of control STAT phosphorylation was determined at each concentration of CP-690,550 by comparison of Ax647 MCF with those from unstimulated and cytokine stimulated controls.
Regulation (control) of Phosphorylation (phosphorylation) of STAT associated with cytokine
2) Confidence 0.05 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC2928212 Disease Relevance 0 Pain Relevance 0.08

General Comments

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