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Context Info
Confidence 0.41
First Reported 1987
Last Reported 1987
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (POMC, INS) cell-cell signaling (POMC, INS) extracellular space (POMC, INS)
extracellular region (POMC, INS) carbohydrate metabolic process (INS) cytoplasm (POMC)
Anatomy Link Frequency
B cells 1
POMC (Homo sapiens)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 2 98.56 Very High Very High Very High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 6 97.40 Very High Very High Very High
Hyperinsulinism 1 95.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acute insulin and glucagon responses to arginine were not increased by beta-endorphin, suggesting that the effect of the opioid on the B cells of the diabetic patients is specific for glucose.
beta-endorphin Neg (not) Positive_regulation (increased) of insulin in B cells associated with diabetes mellitus and opioid
1) Confidence 0.41 Published 1987 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 2951394 Disease Relevance 0.52 Pain Relevance 0.19

General Comments

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