INT324064

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Icam1) cell adhesion (Icam1) plasma membrane (Icam1)
Anatomy Link Frequency
CD86 2
Olfr1328 (Mus musculus)
Icam1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 5 100.00 Very High Very High Very High
Glutamate 1 98.64 Very High Very High Very High
Neuronal nitric oxide synthase 1 94.12 High High
agonist 9 53.32 Quite High
ischemia 9 13.92 Low Low
halothane 4 5.00 Very Low Very Low Very Low
Neurobehavioral 3 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 100.00 Very High Very High Very High
Stroke 17 97.40 Very High Very High Very High
Adhesions 1 90.96 High High
Neurologic Manifestations 8 56.44 Quite High
Targeted Disruption 7 49.76 Quite Low
Cv General 4 Under Development 3 13.92 Low Low
Cv Unclassified Under Development 4 5.36 Low Low
Middle Cerebral Artery Infarction 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Brain Hemorrhage 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, ONO-AE1-259-01 has been suggested to elevate cAMP and inhibit expression of inflammatory molecules such as ICAM-1 and B7.2 (CD86) [28,29], and such inflammatory molecules affect stroke outcomes [30,31].
ONO-AE1-259-01 Negative_regulation (inhibit) of Gene_expression (expression) of ICAM-1 in CD86 associated with inflammation and stroke
1) Confidence 0.02 Published 2010 Journal Exp Transl Stroke Med Section Body Doc Link PMC2912268 Disease Relevance 0.58 Pain Relevance 0.26

General Comments

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