INT324082

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK9) mitochondrion (MAPK9) enzyme binding (CD40)
protein complex assembly (CD40) response to stress (MAPK9) cytoplasm (MAPK9)
CD40 (Homo sapiens)
MAPK9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 99.00 Very High Very High Very High
Spinal cord 39 5.00 Very Low Very Low Very Low
Nerve growth factor 11 5.00 Very Low Very Low Very Low
Glutamate 7 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Glial derived neurotrophic factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 99.00 Very High Very High Very High
Apoptosis 4 94.92 High High
Stress 1 78.44 Quite High
Spinal Cord Injury 53 66.96 Quite High
Injury 33 52.48 Quite High
Death 4 5.00 Very Low Very Low Very Low
Contusions 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low
Lifespan 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and CD40) and cellular stressors activate SAPK, it is possible that hMNP-secreted factors inhibited upstream activators of SAPK thus, attenuating downstream effects such as apoptosis, immune activation, and inflammation.
CD40 Positive_regulation (activate) of SAPK associated with inflammation and apoptosis
1) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912300 Disease Relevance 0.64 Pain Relevance 0.13

General Comments

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