INT324313

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (STC1, UMOD) extracellular region (STC1, UMOD) Golgi apparatus (UMOD)
plasma membrane (UMOD) cell-cell signaling (STC1) cytoplasm (STC1)
Anatomy Link Frequency
kidney 2
STC1 (Homo sapiens)
UMOD (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 4 5.00 Very Low Very Low Very Low
Restless leg syndrome 2 5.00 Very Low Very Low Very Low
Migraine 2 5.00 Very Low Very Low Very Low
endometriosis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Renal Failure 98 100.00 Very High Very High Very High
Prostate Or Kidney Disorder 18 90.32 High High
Lifespan 2 81.48 Quite High
Increased Venous Pressure Under Development 6 75.44 Quite High
Diabetes Mellitus 32 71.16 Quite High
Hypertension 42 70.08 Quite High
Cardiovascular Disease 4 65.20 Quite High
Disease 20 58.40 Quite High
Kidney Stones 38 58.08 Quite High
Crystal Associated Disease 16 40.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, Köttgen et al. [14] published the first genome-wide association study (GWAS) on eGFRcrea, eGFR based on cystatin C (eGFRcys), another measure of kidney function, and CKD, reporting significant association with eGFRcrea at three loci (UMOD, SHROOM3 (GeneID: 57619) and GATM-SPATA5L1 (GeneIDs: 2628 and 79029)), with eGFRcys at two loci (CST3-CST9 (GeneIDs: 1471 and 128822) and STC1 (GeneID: 6781)) and with CKD at one locus (UMOD) [14].
STC1 Binding (published) of UMOD in kidney associated with chronic renal failure
1) Confidence 0.29 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2912386 Disease Relevance 1.61 Pain Relevance 0
Recently, Köttgen et al. [14] published the first genome-wide association study (GWAS) on eGFRcrea, eGFR based on cystatin C (eGFRcys), another measure of kidney function, and CKD, reporting significant association with eGFRcrea at three loci (UMOD, SHROOM3 (GeneID: 57619) and GATM-SPATA5L1 (GeneIDs: 2628 and 79029)), with eGFRcys at two loci (CST3-CST9 (GeneIDs: 1471 and 128822) and STC1 (GeneID: 6781)) and with CKD at one locus (UMOD) [14].
STC1 Binding (published) of UMOD in kidney associated with chronic renal failure
2) Confidence 0.25 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2912386 Disease Relevance 1.62 Pain Relevance 0

General Comments

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