INT324418

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Context Info
Confidence 0.75
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 0.66
Pain Relevance 0

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transport (ITR1) transmembrane transporter activity (ITR1) plasma membrane (ITR1)
transmembrane transport (ITR1)
Anatomy Mention Frequency
filament 6
ITR1 (Saccharomyces cerevisiae)
Pain Term Frequency Confidence Heat
iatrogenic 7 5.00 Very Low Very Low Very Low
Central nervous system 70 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Sprains And Strains 469 94.40 High High
Contagious Ecthyma 7 51.00 Quite High
Cryptococcus Infection 42 50.00 Quite Low
Infection 91 34.16 Quite Low
Repression 7 5.00 Very Low Very Low Very Low
Fungal Meningitis 14 5.00 Very Low Very Low Very Low
Candida Infection 21 5.00 Very Low Very Low Very Low
Coccidioides Infection 7 5.00 Very Low Very Low Very Low
Mycobacterial Infection 14 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While none of the three major virulence factors were significantly altered in these double mutants, mating filament production and sporulation were clearly reduced in bilateral matings of ino1 itr1 × ino1 itr1 and ino1 itr1a × ino1 itr1a double mutants, suggesting that Itr1 and Itr1A are important for inositol transport or sensing (Fig. 6A).
Localization (matings) of itr1 in filament
1) Confidence 0.75 Published 2010 Journal mBio Section Body Doc Link PMC2912663 Disease Relevance 0.09 Pain Relevance 0
While none of the three major virulence factors were significantly altered in these double mutants, mating filament production and sporulation were clearly reduced in bilateral matings of ino1 itr1 × ino1 itr1 and ino1 itr1a × ino1 itr1a double mutants, suggesting that Itr1 and Itr1A are important for inositol transport or sensing (Fig. 6A).
Localization (matings) of itr1a in filament
2) Confidence 0.75 Published 2010 Journal mBio Section Body Doc Link PMC2912663 Disease Relevance 0.09 Pain Relevance 0
While none of the three major virulence factors were significantly altered in these double mutants, mating filament production and sporulation were clearly reduced in bilateral matings of ino1 itr1 × ino1 itr1 and ino1 itr1a × ino1 itr1a double mutants, suggesting that Itr1 and Itr1A are important for inositol transport or sensing (Fig. 6A).
Localization (matings) of itr1a in filament
3) Confidence 0.75 Published 2010 Journal mBio Section Body Doc Link PMC2912663 Disease Relevance 0.09 Pain Relevance 0
While none of the three major virulence factors were significantly altered in these double mutants, mating filament production and sporulation were clearly reduced in bilateral matings of ino1 itr1 × ino1 itr1 and ino1 itr1a × ino1 itr1a double mutants, suggesting that Itr1 and Itr1A are important for inositol transport or sensing (Fig. 6A).
Localization (important) of Itr1 in filament
4) Confidence 0.75 Published 2010 Journal mBio Section Body Doc Link PMC2912663 Disease Relevance 0.09 Pain Relevance 0
While none of the three major virulence factors were significantly altered in these double mutants, mating filament production and sporulation were clearly reduced in bilateral matings of ino1 itr1 × ino1 itr1 and ino1 itr1a × ino1 itr1a double mutants, suggesting that Itr1 and Itr1A are important for inositol transport or sensing (Fig. 6A).
Localization (matings) of itr1 in filament
5) Confidence 0.75 Published 2010 Journal mBio Section Body Doc Link PMC2912663 Disease Relevance 0.09 Pain Relevance 0
While none of the three major virulence factors were significantly altered in these double mutants, mating filament production and sporulation were clearly reduced in bilateral matings of ino1 itr1 × ino1 itr1 and ino1 itr1a × ino1 itr1a double mutants, suggesting that Itr1 and Itr1A are important for inositol transport or sensing (Fig. 6A).
Localization (important) of Itr1A in filament
6) Confidence 0.75 Published 2010 Journal mBio Section Body Doc Link PMC2912663 Disease Relevance 0.09 Pain Relevance 0
PCR was used to screen for ITR gene deletion with primers F4/JH8994 and F3/R3 (see Table S1 in the supplemental material).
Localization (deletion) of ITR
7) Confidence 0.65 Published 2010 Journal mBio Section Body Doc Link PMC2912663 Disease Relevance 0.12 Pain Relevance 0

General Comments

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