INT32444

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Context Info
Confidence 0.22
First Reported 1982
Last Reported 1987
Negated 6
Speculated 0
Reported most in Abstract
Documents 2
Total Number 7
Disease Relevance 0
Pain Relevance 4.47

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extracellular space (Cpe, Pomc) extracellular region (Cpe, Pomc) Golgi apparatus (Cpe)
cell-cell signaling (Pomc) cytoplasm (Pomc) peptidase activity (Cpe)
Cpe (Mus musculus)
Pomc (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 26 100.00 Very High Very High Very High
Neuropeptide 2 96.88 Very High Very High Very High
Opioid 18 94.00 High High
Dynorphin 6 89.44 High High
narcan 3 89.12 High High
opiate 6 54.80 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The antibody displays virtually complete cross-reactivity to met-enkephalin and leu-enkephalin, but no cross-reactivity to beta-lipotropin, alpha-N-acetyl-beta-endorphin and des-Tyr1-beta-endorphin.
enkephalin Neg (no) Binding (cross-reactivity) of beta-endorphin associated with enkephalin
1) Confidence 0.22 Published 1982 Journal Life Sci. Section Abstract Doc Link 6296574 Disease Relevance 0 Pain Relevance 0.70
The antibody displays virtually complete cross-reactivity to met-enkephalin and leu-enkephalin, but no cross-reactivity to beta-lipotropin, alpha-N-acetyl-beta-endorphin and des-Tyr1-beta-endorphin.
enkephalin Neg (no) Binding (cross-reactivity) of beta-endorphin associated with enkephalin
2) Confidence 0.22 Published 1982 Journal Life Sci. Section Abstract Doc Link 6296574 Disease Relevance 0 Pain Relevance 0.70
The antibody displays virtually complete cross-reactivity to met-enkephalin and leu-enkephalin, but no cross-reactivity to beta-lipotropin, alpha-N-acetyl-beta-endorphin and des-Tyr1-beta-endorphin.
enkephalin Neg (no) Binding (cross-reactivity) of beta-lipotropin associated with enkephalin
3) Confidence 0.15 Published 1982 Journal Life Sci. Section Abstract Doc Link 6296574 Disease Relevance 0 Pain Relevance 0.67
The antibody displays virtually complete cross-reactivity to met-enkephalin and leu-enkephalin, but no cross-reactivity to beta-lipotropin, alpha-N-acetyl-beta-endorphin and des-Tyr1-beta-endorphin.
enkephalin Neg (no) Binding (cross-reactivity) of beta-lipotropin associated with enkephalin
4) Confidence 0.15 Published 1982 Journal Life Sci. Section Abstract Doc Link 6296574 Disease Relevance 0 Pain Relevance 0.67
The antibody displays virtually complete cross-reactivity to met-enkephalin and leu-enkephalin, but no cross-reactivity to beta-lipotropin, alpha-N-acetyl-beta-endorphin and des-Tyr1-beta-endorphin.
enkephalin Neg (no) Binding (cross-reactivity) of alpha-N-acetyl-beta-endorphin associated with enkephalin
5) Confidence 0.13 Published 1982 Journal Life Sci. Section Abstract Doc Link 6296574 Disease Relevance 0 Pain Relevance 0.69
The antibody displays virtually complete cross-reactivity to met-enkephalin and leu-enkephalin, but no cross-reactivity to beta-lipotropin, alpha-N-acetyl-beta-endorphin and des-Tyr1-beta-endorphin.
enkephalin Neg (no) Binding (cross-reactivity) of alpha-N-acetyl-beta-endorphin associated with enkephalin
6) Confidence 0.13 Published 1982 Journal Life Sci. Section Abstract Doc Link 6296574 Disease Relevance 0 Pain Relevance 0.69
Met-enkephalin, which comprises the first five amino acids of the beta-endorphin molecule, can also be shown to possess similar biologic activity.
Met-enkephalin Binding (comprises) of beta-endorphin associated with enkephalin
7) Confidence 0.07 Published 1987 Journal J. Lab. Clin. Med. Section Abstract Doc Link 2955065 Disease Relevance 0 Pain Relevance 0.36

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