INT324523

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.98
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4)
cytoplasm (Tlr4)
Tlr4 (Mus musculus)
PGE (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 50 98.80 Very High Very High Very High
cINOD 4 65.04 Quite High
COX2 2 57.20 Quite High
Immobilon 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 50 98.80 Very High Very High Very High
Cancer 86 98.40 Very High Very High Very High
Inflammatory Bowel Disease 22 92.88 High High
Intestinal Cancer 6 87.92 High High
Colorectal Cancer 30 68.84 Quite High
Colitis 134 50.00 Quite Low
Cleidocranial Dysplasia 24 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Polyps 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have previously shown that TLR4-mediated signaling is responsible for mucosal Cox-2 expression and PGE 2 synthesis in the setting of intestinal inflammation [27].
TLR4 Regulation (responsible) of Gene_expression (expression) of PGE associated with inflammation
1) Confidence 0.23 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2912804 Disease Relevance 0.99 Pain Relevance 0.26
We have previously shown that TLR4-mediated signaling is responsible for mucosal Cox-2 expression and PGE 2 synthesis in the setting of intestinal inflammation [27].
TLR4 Regulation (responsible) of Gene_expression (synthesis) of PGE associated with inflammation
2) Confidence 0.23 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2912804 Disease Relevance 0.99 Pain Relevance 0.26

General Comments

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