INT324529

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.48
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PREP) peptidase activity (PREP) nucleus (PREP)
cytoplasm (PREP)
Anatomy Link Frequency
chondrocytes 2
PREP (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 309 100.00 Very High Very High Very High
cytokine 24 60.40 Quite High
Inflammation 48 40.88 Quite Low
Arthritis 24 30.16 Quite Low
metalloproteinase 18 6.68 Low Low
rheumatoid arthritis 12 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Inflammatory stimuli 3 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 312 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 94 95.04 Very High Very High Very High
Targeted Disruption 9 84.88 Quite High
Sexually Transmitted Diseases 1 70.04 Quite High
Stress 3 52.32 Quite High
INFLAMMATION 42 40.88 Quite Low
Arthritis 27 30.16 Quite Low
Infection 14 28.16 Quite Low
Disease 21 23.44 Low Low
Hypertrophy 3 17.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Participants were then asked about their initial commitment to PREP or circumcision using the following question: Are you ready to get circumcised (take PREP) to reduce your risk for getting HIV?
Spec (asked) Negative_regulation (asked) of PREP Binding (commitment) of associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912853 Disease Relevance 0.25 Pain Relevance 0
-induced phosphorylation of both MKK3 and MKK6 in a dose dependent manner with the maximum inhibitory effect of PE being at 50 ?
Negative_regulation (effect) of PE Binding (being) of
2) Confidence 0.12 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991031 Disease Relevance 0.97 Pain Relevance 0.41
g/ml) with the maximum inhibitory effect of PE being at 50 ?
Negative_regulation (effect) of PE Binding (being) of
3) Confidence 0.12 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991031 Disease Relevance 0.63 Pain Relevance 0.32
in human OA chondrocytes has not been reported. p38-MAPK was not activated by treatment with PE alone but pretreatment of human OA chondrocytes with PE selectively inhibited the IL-1?
Negative_regulation (inhibited) of PE Binding (pretreatment) of in chondrocytes associated with osteoarthritis
4) Confidence 0.12 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991031 Disease Relevance 0.63 Pain Relevance 0.32

General Comments

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