INT324530

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.45
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PREP) peptidase activity (PREP) nucleus (PREP)
cytoplasm (PREP)
Anatomy Link Frequency
chondrocytes 2
PREP (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 206 100.00 Very High Very High Very High
Inflammation 32 5.00 Very Low Very Low Very Low
cytokine 16 5.00 Very Low Very Low Very Low
Arthritis 16 5.00 Very Low Very Low Very Low
metalloproteinase 12 5.00 Very Low Very Low Very Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 208 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 94 98.64 Very High Very High Very High
Sexually Transmitted Diseases 1 65.56 Quite High
Targeted Disruption 6 58.64 Quite High
Infection 14 35.36 Quite Low
INFLAMMATION 28 5.00 Very Low Very Low Very Low
Arthritis 18 5.00 Very Low Very Low Very Low
Disease 16 5.00 Very Low Very Low Very Low
Cold Sores 9 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Participants were then asked about their initial commitment to PREP or circumcision using the following question: Are you ready to get circumcised (take PREP) to reduce your risk for getting HIV?
Positive_regulation (circumcised) of Gene_expression (take) of PREP associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.44 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912853 Disease Relevance 0.24 Pain Relevance 0
-induced activation of MKK3 and MKK6 in human OA chondrocytes, cells were pretreated with PE (6.25 to 100 ?
Positive_regulation (induced) of Gene_expression (pretreated) of PE in chondrocytes associated with osteoarthritis
2) Confidence 0.14 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991031 Disease Relevance 0.78 Pain Relevance 0.36
Based on this data the maximum concentration of PE used in these studies was 100 ?
Positive_regulation (Based) of Gene_expression (used) of PE
3) Confidence 0.14 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991031 Disease Relevance 0.43 Pain Relevance 0.22

General Comments

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