INT324575

Context Info Confidence 0.45 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0.04

transport (Trpm5) plasma membrane (Trpm5) biological_process (Trpm5)

Anatomy Link Frequency taste receptor cells 2 Trpm5 (Mus musculus)

Pain Link Frequency Relevance Heat imagery 24 89.52 substance P 6 36.84 qutenza 11 5.00 fifth nerve 2 5.00 addiction 2 5.00 TRP channel 1 5.00 Inflammation 1 5.00 Neurotransmitter 1 5.00 Potency 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 23 77.40 Aging 1 5.00 Body Weight 1 5.00 Dislocations 1 5.00 INFLAMMATION 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In taste receptor cells, stimulation of bitter, sweet and umami substances elevates intracellular Ca2+ levels, leading to activation of TRPM5 [44].

Positive_regulation (leading) of Positive_regulation (activation) of TRPM5 in taste receptor cells

1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912856 Disease Relevance 0.08 Pain Relevance 0.04

General Comments

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