INT324702

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.10
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CGA) protein modification process (PLOD1) small molecule metabolic process (CGA)
extracellular region (CGA) endoplasmic reticulum (PLOD1) cellular nitrogen compound metabolic process (CGA)
PLOD1 (Homo sapiens)
CGA (Homo sapiens)
Pain Link Frequency Relevance Heat
Dismenorea 2 65.32 Quite High
endometriosis 2 62.76 Quite High
adenocard 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis (extended) 78 98.16 Very High Very High Very High
Cancer 38 93.16 High High
Dysmenorrhea 2 65.32 Quite High
Breast Cancer 2 59.36 Quite High
Malignant Neoplastic Disease 8 52.08 Quite High
Metastasis 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Aneuploidy 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We showed that human recombinant (hr) LH (as well as hCG) induced a significant increase in cell invasiveness through Matrigel-coated porous membranes in the human EC cell line Hec1A, which expresses the LH/hCG-R.
LH Positive_regulation (increase) of hCG associated with endometriosis (extended)
1) Confidence 0.03 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2913851 Disease Relevance 1.10 Pain Relevance 0.10
In this tissue, LH/hCG apparently acts through the LH/hCG-R-dependent activation of both the c-AMP and phospholipase C transduction pathways [20, 21].
LH Positive_regulation (activation) of hCG
2) Confidence 0.01 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2913851 Disease Relevance 0 Pain Relevance 0

General Comments

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