INT324758

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tlr7) signal transduction (Tlr7) endoplasmic reticulum (Tlr7)
plasma membrane (Tlr7) intracellular (Tlr7) lysosome (Tlr7)
Tlr7 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 67 52.48 Quite High
cytokine 14 48.04 Quite Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 1 100.00 Very High Very High Very High
Shock 4 64.04 Quite High
INFLAMMATION 69 52.48 Quite High
Necrosis 3 24.72 Low Low
Viral Infection 1 19.92 Low Low
Disease 36 8.56 Low Low
Injury 15 5.00 Very Low Very Low Very Low
Sepsis 10 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 7 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, emerging data support the activation of TLR7 and 8 by antiphospholipid antibodies (APL) isolated from patients with APL syndrome [32, 33], as has been also shown previously for TLR2 and 4 [34–36].
Negative_regulation (previously) of Positive_regulation (activation) of TLR7 associated with syndrome
1) Confidence 0.21 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913853 Disease Relevance 0.22 Pain Relevance 0.03

General Comments

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