INT324772

Context Info Confidence 0.49 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.41 Pain Relevance 0.29

protein folding (Hspd1) cytosol (Hspd1) mitochondrion (Hspd1) extracellular space (Hspd1) Golgi apparatus (Hspd1) cytoplasm (Hspd1)

Anatomy Link Frequency macrophages 2 Hspd1 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 14 88.96 monoamine 1 83.52 Inflammatory response 5 77.52 Inflammatory mediators 1 59.64 metalloproteinase 1 57.64 chemokine 1 53.08 Inflammation 67 50.68 agonist 2 26.40 rheumatoid arthritis 7 5.00 Multiple sclerosis 4 5.00

Disease Link Frequency Relevance Heat Apoptosis 2 84.84 Injury 15 80.00 INFLAMMATION 69 77.52 Adhesions 1 53.48 Disease 36 5.00 Sepsis 10 5.00 Rheumatoid Arthritis 7 5.00 Systemic Lupus Erythematosus 6 5.00 Infection 6 5.00 Arthritis 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

production in murine macrophages and in mHSP60-expressing COS1 cells, were shown to differentially activate APC function.

Positive_regulation (activate) of Gene_expression (expressing) of HSP60 in macrophages

1) Confidence 0.49 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913853 Disease Relevance 0.41 Pain Relevance 0.29

General Comments

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