INT324816

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.59
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein folding (Hspd1) cytosol (Hspd1) mitochondrion (Hspd1)
extracellular space (Hspd1) Golgi apparatus (Hspd1) nucleus (Ik)
Hspd1 (Mus musculus)
Ik (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 28 100.00 Very High Very High Very High
Inflammation 134 93.60 High High
Multiple sclerosis 8 42.44 Quite Low
rheumatoid arthritis 14 37.80 Quite Low
Inflammatory response 10 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Nicotine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 8 100.00 Very High Very High Very High
INFLAMMATION 138 93.60 High High
Disease 72 62.84 Quite High
Atherosclerosis 6 56.80 Quite High
Cancer 6 56.00 Quite High
Demyelinating Disease 8 42.44 Quite Low
Diabetes Mellitus 2 41.32 Quite Low
Inflammatory Bowel Disease 4 40.60 Quite Low
Systemic Lupus Erythematosus 12 39.24 Quite Low
Rheumatoid Arthritis 14 37.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The first report of a putative endogenous activator of TLRs dates back to 2000, when heat shock protein 60 (HSP60) was shown to induce cytokine synthesis through TLR4 activation [12].
HSP60 Positive_regulation (induce) of Gene_expression (synthesis) of cytokine associated with shock and cytokine
1) Confidence 0.00 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913853 Disease Relevance 0.79 Pain Relevance 0.25
The first report of a putative endogenous activator of TLRs dates back to 2000, when heat shock protein 60 (HSP60) was shown to induce cytokine synthesis through TLR4 activation [12].
heat shock protein 60 Positive_regulation (induce) of Gene_expression (synthesis) of cytokine associated with shock and cytokine
2) Confidence 0.00 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913853 Disease Relevance 0.80 Pain Relevance 0.25

General Comments

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